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I fully expect every pharmacy in the country to pull it off the shelf. "They", meaning the FDA will sequester it. My cynical conspiratorial self figures they will come back in a month or two with a cure that involves something similar, but not the same. It will have a trivial molecule change that can be re-patented so they can charge $2000 per treatment. Just like that, something that cost the rest of the world $15 bucks will cost us a $100 co-pay or full boat if you have an HDHP and our insurance companies will pass the cost on to everyone. "WE CURED IT, THOSE STINKY FRENCH HAD THE RIGHT IDEA, BUT WE MADE IT BETTER". Yeah, you sure did.

Schmidt's yes. Schlitz no. Yuengling always. Now that I'm half Skook.

That's why you hafta add the White Castle. It's homeopathy. "Like cures like" or something like that.

Murphy said they're still working on the list of what's 'non-essential'. TBD. I just bought two cases of beer. I have my priorities straight.

Im sorry, who the fuck are you again?

Why are you stressing over WATER ?- it is not going off anytime soon...........if it goes off - your few cases will not help you survive.... Do you have a well? Do you have a genny? do you have gas on hand? If you do you have water. The drugs will be available for those that need it - if you are not sick, you wont need it, so no worry about getting it. Let's get some perspective here - like with the testing - they need to test the symptomatic first to filter out the Flu patients, then once the Flu fizzles a bit they can sort those from the covid folks - *then* with more testing they get find those that have no viral load and those that have it but have no symptoms.... If you have NO symptoms at this time there is no reason to test you, in a perfect world you would be, but we cannot at this time Not my quotation - " Do not worry about what you do not know - worry about what you can control..."

There is a pharma/biopharma blog that has long been followed closely by many in the pharma industry, and outside. There is usually just a single post per day on whatever topic the author, a senior medicinal chemist at a Boston pharma company, deems most relevant at the moment. The author does a great job of making the science, and the industry insights, accessible to a wide audience. He also usually links back to the primary literature, for those who want to get more down in the weeds in a topic. Most of the comments are pretty good as well; a lot of the posters are directly or indirectly involved in the work being described. Most of what is contained in the blog posts on the coronavirus and COVID-19 are already being discussed on this board, but these summaries are great, and may contain some new nuggets of information. The blog is: In the Pipeline Recent posts on the novel coronavirus and the COVID-19 disease include: COVID-19 Small Molecule Therapies Reviewed COVID-19 Biologic Therapies Reviewed Time Scales, Viral and Human Angiotensin and the Coronavirus Coronavirus: Some Clinical Trial Data Chloroquine past and present (added 3/20) The Latest Coronavirus Clinical Trials (added 3/24) Comparing Hydroxychloroquine Trials (added 3/31)

2 you need to step up your game.

You come in my house uninvited and you’re going out on a stretcher at best.

Schlitz and White Castles will most likely kill you anyways so you have that going for you

…. and here goes his girlfriend.....to back him up.

I think this guy is drinking his 30 year old Tang that he found in his basement bomb shelter.

MD's prescribe off-label all the time. It can be hard to get insurance to cover off-label prescriptions, and I understand that, but chloroquine is off-patent and cheap. To add the novel coronavirus as an indication, they might be able to skip phase 1 clinical trials altogether, since those have already been done, unless they want to change the demographics of the trial, perhaps to include an older population. Phase 2 trials would take time, but wouldn't have to be large, since the therapeutic index for chloroquine is pretty narrow--they wouldn't be testing a wide range of doses. Phase 3 would still be phase 3, big, expensive and slow...

Indeed. What the head of the FDA was saying today......but not saying... ..is that people are getting that drug now.....as volunteers under the compassionate care protocol.....and the data is being gathered ....now. I understand his reluctance to spell it out. The FDA’s primary mission is to protect Americans. But given the need to get ahead of this, bypassing some safety protocols is warranted. Especially since we already know a remarkable amount about this drug.

Wow! I have not seen that old code in years! Be careful with 'tl;kgmg poglkg, even though technically legal, most street Cops will give you grief if they see them! Where did you find the Vvm' t[gpomgt? I have looked everywhere and they are out of stock!

I bought ammo and mags 3 panics ago. I'm going to sit this one out.

I am scratching my head at this thread, your posts and your options. I would avoid the "less than ideal" choices you laid out. I would simply buy a pump shotgun in 12 gauge and roll with that. And since you are a southpaw like me, get a Mossberg 500. Ambi controls. Cheap ammo, reliable, easy to maintain and simple to learn. Plus 12 gauge is king for home defense. All other calibers fall short.

Do you have children in your home? If the answer is no, why are you locking your firearms in a safe when you are there? I have firearms in several places. Nightstand being one of them. I do have a safe for other times. I also have a .44 magnum downstairs in case a bear enters the home again. It happened in 2007 and I put bars over that window. We tore that part off the house and I did not replace the bars and the new window is higher. It could get another bear, so if Yogi gets in again, Yogi dies.

First Rule of Fight Club: DON'T TALK ABOUT FIGHT CLUB!!! Troll much? ~R

If I step up my game I won't be able to step up on the scale.

Goodness! I was busy with other things today (no, not digging a bunker...) and I come back to this train wreck of a thread. Folks, please... the sky is not falling. I know some of you probably have bored kids underfoot that are making you bonkers, as you anxiously audit your food supplies and rounds... (and, on a serious note, a few of you even have legitimate exposure concerns)… but for goodness sakes, a few of you just need to calm the heck down! Knock it off with the insults and personal attacks. It'd be a shame to push this over to the 1A Lounge, but I may have to do that. Last warning! I mean, sheesh... as Mom used to say: can't we all take a nice ride in the car without you kids acting up and ruining things for everyone?!

It's here... make your last minute runs..

Schlitz gives you the shitz!

Looks like it's gonna be Schlitz and White Castle for the next 2 months. The living will envy the dead. Godspeed, everyone!

Just more last minute sheeple charlies............GOD I love being in the sticks

I've heard from two more reliable sources, it's coming, probably by Sunday. Essential services will be open (grocery stores and medical related businesses). Any non-essential businesses will be told to close. Essential personnel (utility workers, LEO, certain .gov workers, etc. ) will still be working. Just watch the run on grocery stores and liquor stores this weekend...

A few moments ago I was walking through our Cafeteria and I caught a few second of Murphy talking about "tightening the screws" about social distancing. We will hear more about it tomorrow morning.

3 Espressos today from the Bialetti - TOOO MUCH !!!!

Just a heads up, coming here momentarily by Murphy... ....."The morning after California laid out the most restrictive measures to combat the virus in the US, NY Gov. Andrew Cuomo on Friday laid out new measures for New York State to combat the coronavirus outbreak, imposing new restrictions like ordering "100% of the workforce" to stay home. During this time, Cuomo is order all businesses in the state that aren't deemed "essential" to close, and added that though public transit will remain open for people who need it to travel to their 'essential' jobs, and to get to places like hospitals and doctors offices and grocery stores and pharmacies, he urged New Yorkers to only take the trains if absolutely necessary. He threatened to fine businesses and individuals caught breaking the rules. "These are not helpful hints...they will be enforced. There will be a civil fine and mandatory closure for any business that is not in compliance.

I inferred that you were by your statement - good don't stress Can you as non doctor, prescribe medicines? Do non-doctors have access to prescription only medicines? If no to either, how can anyone hoard? I am just trying to rationalize and understand statements that to me seem odd to me. I find that the usage of pronouns, especially like 'they', really muddies the waters - they being whom? Normal Citizens? Not trying to pick a fight, I just don't see citizens being able to hoard a prescription drug - see the idiots trying to get the aquarium form of it - some will probably take it - ... darwinism at it's finest.

I am not a leo...never been in the two way range...dont wanna be... and i am NOT going to fight fair... Also most don't realize frog brain on adrenal dump, and what it does to them, there.is no way they are entering a code at o dark 30 when the crash happens..... Also.. My stairs from the front door have two gates across them....one at the bottom and one at the top both latching from when my babies were babies..never removed them...they are now well positioned obstacles for an attacker...slow him down enough to catch buckshot in the chest

Pepper...wild ass crazy boxer.... she is 6 and a firebrand hates most everyone and everything except her pack....she does a good job

I like your optimism :)

Funny thing is no one that I've talked to up here has ever heard of him. Granted hes about 2 hours south of me but still my local gun shop owner has never heard of him, the only sporting Clay's range owner has never heard of him, even the guys at green mountian barrel works have never heard of him. Kinda strange

You crochet and your left handed and you don't like AR s

…. it's our fault as NJ residents, we let it get this far.....omo.

Uhhhh.... Dont like hand guns... ok fine. But why on earth would you limit yourself to these guns for self defense? Which use handgun rounds btw If you want reliable and simple get a pump action shotgun. You want real home defense, ar15 all day.. Contrary to popular belief people buy ar15's because they are just that good for self defense... another than the 22 you listed it has about the same felt recoil as 357 or 45lc You will get many experienced opinions in here, do not discount something because you associate some kind of image with it. 357 is not cheap and neither is 45lc ammo

I hope their warehouse burns down

Anyone know where I can get 30 round magazine?

When you legally hunt turkey, I recommend a healthy dose of coppered #5's.