Definitely try out the Walther before buying, my wife fell in love with the M&P 380 EZ, she is very small with small hands, the M&P was much easier for her to manipulate. She also wanted a .22 once I told her how much the .380 ammo was and that once she went through tho 1k rounds I bought for her she was on her own. She tried the Walther .22 but ultimately felt the Ruger SR22 was a better fit for her, she loves that gun also.
The Ruger 10/22 is an awesome rifle, everyone should own one, it’s a ton of fun to shoot and doesn’t break the bank to go through a couple hundred rounds.