Excellent! You know the full route, right? i-78 W--> I-81 S --> I-77 S (just past Roanoke and through VA, NC and SC). I used to stop off in Richburg, SC. If you can, you might want to make a quick stop right as you cross the SC State Line from NC. There's a huge Cabela's right there on the State line. It's only 3 years old.
Furthermore, I-77S (down to Columbia) ---> I-26 E --> back onto i-95 S). If you want a good place to stop for fuel and lunch in SC, after you get back onto I-95, stop off in Walterboro (Ex. 57 - SC highway 64 E). Proceed on SC 64 E, for a mile or so to Robertson Blvd. Left onto Robertson Blvd, and the follow Robertson Blvd across US 15/501. After you cross, look for "Dukes BBQ" on the left. The best BBQ around the area and it's served Buffet Style ~$12,00, all you can eat. Pulled Pork, Fried chicken, Ribs, and excellent southern sides. But be careful when you travel there. It's closed on Mon-Tues. but open Wed - Sun. If you go through on Sun, get there before 11am, because it will fill up quickly with the Sunday brunchers that are just coming out of Church. Also, they close early on Sun. (at 2pm). They're open until 9p on all the other days they're open.
Also, if you have the choice of stopping for fuel in NC vs SC, pick SC. Cheaper fuel/taxes.