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I fully expect every pharmacy in the country to pull it off the shelf. "They", meaning the FDA will sequester it. My cynical conspiratorial self figures they will come back in a month or two with a cure that involves something similar, but not the same. It will have a trivial molecule change that can be re-patented so they can charge $2000 per treatment. Just like that, something that cost the rest of the world $15 bucks will cost us a $100 co-pay or full boat if you have an HDHP and our insurance companies will pass the cost on to everyone. "WE CURED IT, THOSE STINKY FRENCH HAD THE RIGHT IDEA, BUT WE MADE IT BETTER". Yeah, you sure did.

Schmidt's yes. Schlitz no. Yuengling always. Now that I'm half Skook.

That's why you hafta add the White Castle. It's homeopathy. "Like cures like" or something like that.

Murphy said they're still working on the list of what's 'non-essential'. TBD. I just bought two cases of beer. I have my priorities straight.

Im sorry, who the fuck are you again?

Why are you stressing over WATER ?- it is not going off anytime soon...........if it goes off - your few cases will not help you survive.... Do you have a well? Do you have a genny? do you have gas on hand? If you do you have water. The drugs will be available for those that need it - if you are not sick, you wont need it, so no worry about getting it. Let's get some perspective here - like with the testing - they need to test the symptomatic first to filter out the Flu patients, then once the Flu fizzles a bit they can sort those from the covid folks - *then* with more testing they get find those that have no viral load and those that have it but have no symptoms.... If you have NO symptoms at this time there is no reason to test you, in a perfect world you would be, but we cannot at this time Not my quotation - " Do not worry about what you do not know - worry about what you can control..."

There is a pharma/biopharma blog that has long been followed closely by many in the pharma industry, and outside. There is usually just a single post per day on whatever topic the author, a senior medicinal chemist at a Boston pharma company, deems most relevant at the moment. The author does a great job of making the science, and the industry insights, accessible to a wide audience. He also usually links back to the primary literature, for those who want to get more down in the weeds in a topic. Most of the comments are pretty good as well; a lot of the posters are directly or indirectly involved in the work being described. Most of what is contained in the blog posts on the coronavirus and COVID-19 are already being discussed on this board, but these summaries are great, and may contain some new nuggets of information. The blog is: In the Pipeline Recent posts on the novel coronavirus and the COVID-19 disease include: COVID-19 Small Molecule Therapies Reviewed COVID-19 Biologic Therapies Reviewed Time Scales, Viral and Human Angiotensin and the Coronavirus Coronavirus: Some Clinical Trial Data Chloroquine past and present (added 3/20) The Latest Coronavirus Clinical Trials (added 3/24) Comparing Hydroxychloroquine Trials (added 3/31)

2 you need to step up your game.

You come in my house uninvited and you’re going out on a stretcher at best.

Schlitz and White Castles will most likely kill you anyways so you have that going for you

…. and here goes his girlfriend.....to back him up.

I think this guy is drinking his 30 year old Tang that he found in his basement bomb shelter.

MD's prescribe off-label all the time. It can be hard to get insurance to cover off-label prescriptions, and I understand that, but chloroquine is off-patent and cheap. To add the novel coronavirus as an indication, they might be able to skip phase 1 clinical trials altogether, since those have already been done, unless they want to change the demographics of the trial, perhaps to include an older population. Phase 2 trials would take time, but wouldn't have to be large, since the therapeutic index for chloroquine is pretty narrow--they wouldn't be testing a wide range of doses. Phase 3 would still be phase 3, big, expensive and slow...

Indeed. What the head of the FDA was saying today......but not saying... ..is that people are getting that drug now.....as volunteers under the compassionate care protocol.....and the data is being gathered ....now. I understand his reluctance to spell it out. The FDA’s primary mission is to protect Americans. But given the need to get ahead of this, bypassing some safety protocols is warranted. Especially since we already know a remarkable amount about this drug.

Wow! I have not seen that old code in years! Be careful with 'tl;kgmg poglkg, even though technically legal, most street Cops will give you grief if they see them! Where did you find the Vvm' t[gpomgt? I have looked everywhere and they are out of stock!

I bought ammo and mags 3 panics ago. I'm going to sit this one out.

I am scratching my head at this thread, your posts and your options. I would avoid the "less than ideal" choices you laid out. I would simply buy a pump shotgun in 12 gauge and roll with that. And since you are a southpaw like me, get a Mossberg 500. Ambi controls. Cheap ammo, reliable, easy to maintain and simple to learn. Plus 12 gauge is king for home defense. All other calibers fall short.

Do you have children in your home? If the answer is no, why are you locking your firearms in a safe when you are there? I have firearms in several places. Nightstand being one of them. I do have a safe for other times. I also have a .44 magnum downstairs in case a bear enters the home again. It happened in 2007 and I put bars over that window. We tore that part off the house and I did not replace the bars and the new window is higher. It could get another bear, so if Yogi gets in again, Yogi dies.

First Rule of Fight Club: DON'T TALK ABOUT FIGHT CLUB!!! Troll much? ~R

Imo, Beyer donated all those pill for a reason.. they want what ever government contract is being put together for medical treatment.. if their drug dominates clinical studies.. well that's the name that gets printed on all the literature. If their "novel" form of a generic drug shows promise, the government is more likely to fast track the drugs approval and give them all the money to supply meds.. its get "on label" perscibing authority and the rest is history. Since our government loves to waste money, and loves the pharma industry... my guess is it will work.

If its approved for a condition, it's "on' label.. If it's not listed as an approved FDA treatment, it doesnt matter how similar it is.. it's off label. There is nothing to be confused here, a doctor can write a prescription off label for anything if they feel its medically appropriate. There are drugs out there being used for psychiatric condition's that are not FDA approved for mental health at all, or unrelated mental health disorders. Similarity has nothing to do with this. Doctors read clinical studies all the time to keep up with how a drug can be used to treat a patient, if there is good data on a alread FDA approved drug.. nothing says they cant use it. There is no confusion. The APPROVED drug can be prescribed off label.. if Bayer wants to produce a novel form of the drug to repatent it... that's their business but the government can still solicit any number of pharmaceutical companies to produce the generic APPROVED form. And why wouldnt a company jump on that?

I inferred that you were by your statement - good don't stress Can you as non doctor, prescribe medicines? Do non-doctors have access to prescription only medicines? If no to either, how can anyone hoard? I am just trying to rationalize and understand statements that to me seem odd to me. I find that the usage of pronouns, especially like 'they', really muddies the waters - they being whom? Normal Citizens? Not trying to pick a fight, I just don't see citizens being able to hoard a prescription drug - see the idiots trying to get the aquarium form of it - some will probably take it - ... darwinism at it's finest.

I am not a leo...never been in the two way range...dont wanna be... and i am NOT going to fight fair... Also most don't realize frog brain on adrenal dump, and what it does to them, there.is no way they are entering a code at o dark 30 when the crash happens..... Also.. My stairs from the front door have two gates across them....one at the bottom and one at the top both latching from when my babies were babies..never removed them...they are now well positioned obstacles for an attacker...slow him down enough to catch buckshot in the chest

I wonder how many people here have actually ran through a practice drill where they had to get something out of their safe to defend themselves quickly? I doubt many...

Pepper...wild ass crazy boxer.... she is 6 and a firebrand hates most everyone and everything except her pack....she does a good job

What....no attack dog???

Chloroquine is also used for the treatment of lupus, but for a different reason. This drug is pretty remarkable in terms of how many ways it affect cellular processes in the human body. It looks pretty promising as a treatment for corona virus. I hope they get enough clinical data pretty damn quick.

I like your optimism :)

Here's what I'm doing. sdl;kj nsdlfv sd;lkfne kfn ;wkjkrj ig;lh,h r;rlgkg'g 'tl;kgmg poglkg,v 'tk;lgm t'ktmkg mgvG Vvm' t[gpomgt I feel very safe.

Funny thing is no one that I've talked to up here has ever heard of him. Granted hes about 2 hours south of me but still my local gun shop owner has never heard of him, the only sporting Clay's range owner has never heard of him, even the guys at green mountian barrel works have never heard of him. Kinda strange

The guns people used to own before the boating accident.

Popular beer rebranded.

"You mean I can't buy a gun online and ship it to my house?" "Why do you need references, I don't want people to know I am buying a gun." "Why does this take 3 months, I never committed a crime?" "It's easier to buy a brand new car off the lot than to get this permit."

You crochet and your left handed and you don't like AR s

Everyone has to do what makes them comfortable. I'm not at the point yet where I feel I need to carry at home. That may change, it may not. I do revisit that idea often. I would just stress/ask everyone to be smart, diligent and SAFE. The current state of affairs make the basic rules of firearm safety MORE important, not less. The last thing we need are more statistics for the antis.

…. it's our fault as NJ residents, we let it get this far.....omo.

am currently looking at 3 options: Rossi Circuit Judge 45lc/410 ---Its an expensive novelty, with many associated problems that you are unaware of; including gasses escaping at the cylinder/barrel connection. There's a reason that gun mfgrs did not go down this path...forget it. Rossi Model 92 357/38 special ---Nice lever gun. I have one myself. It's also a bit of a novelty, as it doesn't fit into any category well. It's also not particularly easy to shoot...lever guns do take time to learn. Not a very common rifle either, and relatively expensive when you do find one. It is however a nice companion for a 38 or 357 revolver. Henry H001 22s/22l/22lr ---Beautiful, well-made, and relatively expensive rifle (for what it is). Levers are an acquired taste. A .22 lever rifle's greatest advantage is cheap shooting. For home defense? A decided 'meh'. I What would I recommend? That's kinda tough, as you haven't given us a whole lot of info to work with here. Don't like semi-autos, don't like handguns. Haven't shot much at all, and just got into the arena because the world is getting crazy. Hmmm...to just have "something" around, that doesn't cost much or take much training or practice to 'defend the realm'...ugh....A difficult question. First -- do you realize what you're getting into? In NJ, even carrying a rifle/shotgun outside the home can be considered assault; depending on what you're doing. You need to get yourself informed. These aren't toys, and this isn't the movies or tv. It's a sobering topic to think about. A cheap and easy primer would be one of Evan Nappen's lectures. Yes, he is trying to sell a pre-paid legal plan, but you don't have to buy into that...he does cover the legal aspects (and potential pitfalls) well. Second....what do you plan to do with this firearm? It does matter. If you want to have something, and might want to take up hunting or shooting trap/skeet/sporting clays ....you want a shotgun. If you want to take-up paper target shooting...you want a rifle.take Third ... Who is going to be shooting this firearm? Just you? You and the wife? Kids? It all plays into answering the question. the answer of "what to recommend" hinges on these and other related questions. Without further info....I'd say a pump shotgun is more what you need.

Uhhhh.... Dont like hand guns... ok fine. But why on earth would you limit yourself to these guns for self defense? Which use handgun rounds btw If you want reliable and simple get a pump action shotgun. You want real home defense, ar15 all day.. Contrary to popular belief people buy ar15's because they are just that good for self defense... another than the 22 you listed it has about the same felt recoil as 357 or 45lc You will get many experienced opinions in here, do not discount something because you associate some kind of image with it. 357 is not cheap and neither is 45lc ammo

I hope their warehouse burns down

I bought two thirty round magazines this week- one had PBR and the other Miller Lite. Also a 12 round magazine loaded with Yuengling. I already have 12 round mags with Molsen in my bunker.

Anyone know where I can get 30 round magazine?

When you legally hunt turkey, I recommend a healthy dose of coppered #5's.